Saxenda® (Liraglutide)

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  • Saxenda

    Saxenda® (Liraglutide)


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    •  How To Use
    •  Box Warning

      Saxenda (liraglutide) carries a boxed warning regarding the risk of thyroid C-cell tumors. This warning is based on findings from animal studies, where liraglutide caused dose-dependent and treatment-duration-dependent thyroid C-cell tumors in both genders of rats and mice. It's important to note, however, that the relevance of these findings to humans has not been determined. Therefore, it is not clear whether Saxenda causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in humans.

      Due to this potential risk, Saxenda is contraindicated in patients with a personal or family history of MTC, as well as in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Patients using Saxenda are advised to be aware of the potential risk of MTC and to watch for symptoms of thyroid tumors, such as a mass in the neck, difficulty swallowing, shortness of breath, or persistent hoarseness. However, routine monitoring of serum calcitonin or using thyroid ultrasound for early detection of MTC in patients treated with Saxenda is considered of uncertain value.

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      Saxenda® (Liraglutide)


      Ask a Pharmacist

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      Medically Reviewed by

      Dr. Aaron L Wiegmann (MD, MS)

      Active Ingredient:Liraglutide
      Warnings:Possible thyroid tumors, including thyroid cancer
      Drug Type:GLP-1 receptor agonist
      Used For:Weight Loss
      Administration:Subcutaneous Injection
      Available Strengths:0.6mg, 1.2mg, 1.8mg, 2.4mg and 3.0mg
      Storage:Store unused pens in the refrigerator between 36°F and 46°F (2°C to 8°C). The product should be stored between 59°F and 86°F (15°C and 30°C) after use
      Manufacturer:Novo Nordisk

      What is Saxenda?

      Saxenda is an injectable weight-loss drug. It aims to help people lose weight and prevent them from gaining weight. This prescription medication is used for adults with excess BMI and weight-related health issues or obesity, but it can also be used in older children (aged 12-17 years) facing the same issues. Its active ingredient is liraglutide, the same active ingredient in Victoza. It is in the same drug class as semaglutide. Both semaglutide and liraglutide are a kind of drug called glucagon-like peptide-1 (GLP-1) agonists.

      The human body naturally produces GLP-1, a hormone that helps regulate hunger.

      Glucagon-like peptide-1 agonists, including Saxenda, help patients feel less hungry and consume fewer calories. This class of drugs also slows stomach emptying, reducing feelings of hunger. This allows patients who take Saxenda and drugs like it to battle obesity

      Saxenda Cost & Coupons

      In America, Saxenda can vary widely in price without insurance depending on factors such as pharmacy, location, and discounts or coupons. Several health insurance companies do not cover Saxenda pens on their plans, as they do not consider weight loss medicines eligible for coverage. It’s not uncommon for Americans to pay upwards of $1,300 to $1,500 for a month’s supply of Saxenda without insurance. Due to the massive price of Saxenda pens, Americans have to start lookinmg to buy Saxenda from Canada and Mexico.

      Americans can buy Saxenda online from Canada for a fraction of the cost through Diet Pens. Purchasing Saxenda through Diet Pens is the same as purchasing it from your local pharmacy; you will receive the same brand-name (Novo Nordisk) medication.

      If this is your first time buying Saxenda online through Diet Pens, take advantage of their DIET10 discount code. With this coupon, you can save 10% on your first order of Saxenda pens.

      How Do I Use Saxenda?

      Read the directions you receive from your doctor and your pharmacy thoroughly. Follow these directions and the patient information, medication guides, and instruction sheets you receive.

      Patients usually take Saxenda injections once a day. It is injected under the skin on the following body parts: the stomach area or abdomen, upper thigh, or upper arm. You should inject the medicine in a different part of your body every day. Do not repeat injections in the same area twice.


      You can inject your Saxenda dose at any time of day and take it with or without food, whatever you prefer.

      Your doctor should show you how to use your Saxenda pen before you do it alone. Be sure you understand how to safely perform the injection and dispose of all parts before you try it.

      If you notice your Saxenda pen has changed colors or appears to have particles in it, do not use it.

      Request a pharmacy consultation if you need additional help with your Saxenda pen. One of our licensed pharmacists will be more than happy to assist you. 

      Saxenda Side Effects

      Saxenda’s most common side effects are as follows:

      • Nausea
      • Diarrhea
      • Constipation
      • Vomiting
      • Injection Site Reactions
      • Low Blood Sugar
      • Headache
      • Tiredness
      • Dizziness
      • Stomach Pain
      • Lipase Level Changes

      Like any GLP-1 agonist drug, Saxenda for weight loss can cause serious side effects, though not every patient will have these side effects. Saxenda’s possible side effects include:

      • Pancreatitis, or pancreas inflammation: If you have persistent abdominal pain or vomiting, stop taking your prescribed Saxenda and call your doctor immediately.
      • Gallbladder issues: Saxenda pens can cause gallbladder issues, including gallstones. Contact your doctor if you have the following symptoms: upper abdominal pain, jaundice, fever, or clay-colored feces.
      • Increased heart rate: People taking this drug may experience an increased heart rate while resting. Contact your doctor if you notice your heart racing for several minutes.
      • Kidney problems or kidney failure: When you take Saxenda, you may experience diarrhea, nausea, or vomiting, which leads to dehydration. Dehydration is a cause of kidney failure, which may lead to the need for dialysis. This illness can happen in people who have never had kidney problems before taking Saxenda. Alert a doctor if you are experiencing diarrhea, nausea, or vomiting that isn’t going away or can’t drink liquids by mouth.
      • Serious allergic reactions: You may have a severe allergic reaction if your symptoms include swelling of the face, lips, nose, and throat, fainting, dizziness, rapid heartbeat, severe rash, itching, and breathing or swallowing problems.
      • Depression or suicidal thoughts: People who take Saxenda for diabetes or weight loss, may notice mental changes. If you have any alterations to your mood that worry you, tell your doctor.
      • An increased risk of low blood sugar, especially in adults with type 2 diabetes who also take type 2 diabetes medications like insulin or sulfonylureas.

      If you have low blood sugar, your symptoms may include headaches, shakiness, weakness, sweating, drowsiness, dizziness, confusion, irritability, hunger, a fast heartbeat, and jitters. Patients taking prescribed Saxenda should monitor their blood sugar before and during medication use.

      Warnings and Precautions

      Saxenda and Victoza should not be used together. They are both used with diet and exercise to treat type 2 diabetes and weight loss. 

      Several groups of people should refrain from taking Saxenda. These people include:

      • Those diagnosed with multiple endocrine neoplasia type 2, a disorder in which people have tumors
      • People who have a history, personal or family, of medullary thyroid cancer
      • People who have insulin-dependent diabetes
      • People who have diabetic ketoacidosis
      • People who are pregnant

      Studies conducted testing liraglutide on animals caused thyroid tumors or thyroid cancer. Nobody knows whether this is a risk for people who use Saxenda pens in regular doses.

      Please call your doctor right away if you discover the symptoms of a thyroid tumor, including swelling or a lump in your neck.

      You should not use Saxenda if prescribed insulin or other liraglutide medicines like albiglutide, dulaglutide, exenatide, Byetta, Bydureon, Tanzeum, or Trulicity.

      Drug Interactions With Saxenda

      Talk to your prescribing doctor if you have questions about taking Saxenda pens with your other medications. It’s crucial to tell your doctor about any other medications you are taking, including any vitamins and supplements.

      Prescription Saxenda has been found to have interactions with over 200 different medications. Most interactions are moderate, two are central, and the rest are minor. The two drugs that have significant interactions with Saxenda are bexarotene and gatifloxacin.

      Interaction between Saxenda and Bexarotene

      Bexarotene is a type of cancer medication known as a retinoid. Its brand name is Targretin. If you take both bexarotene and Saxenda, you may be more likely to get a disease of the pancreas called pancreatitis. To prevent this interaction, your doctor may prescribe an alternative medication, a smaller dose, or order more frequent monitoring to ensure safe use.

      Warning signs to look for include chronic nausea, vomiting, tenderness in the abdomen, and upper abdominal pain, especially if it wraps to your back or worsens after you eat. Contact your physician immediately if you are taking both medications and have these symptoms.

      Interaction between Saxenda and Gatifloxacin

      Gatifloxacin is an ophthalmic medication used to treat eye infections. The medication is suspended in eye drops. Its brand name is Zymaxid. It can change how much glucose is in the blood, so people with diabetes shouldn’t take it. There have been reports of low and high blood sugar in patients taking both drugs. Those who were taking Gatifloxacin and had severe cases of hypoglycemia have gone into comas and even died.

      Strengths and Dosages

      Saxenda is a once-daily injection pen. When you take your Saxenda from Canada, your daily dose will be 0.6mg. Saxenda is a daily prescription, rather than a weekly dose, to help reduce gastrointestinal side effects, according to

      Your dosage increases weekly by .6mg until it reaches 3mg, the maximum dose in the Saxenda pen.

      You should never share your Saxenda pen with anyone, even if you have changed the needle. Serious infections can be spread by sharing needles or injection pens.


      FAQs helps Americans purchase Saxenda at a discounted rate, with two easy steps:

      1. Add your pen to your cart and proceed to checkout. 

      2. Ensure a valid prescription is attached to your order. 

      We can try! Some pharmacies do not send prescriptions to mail-order pharmacies, while others do. We want you to know that our team will try our best to obtain the transfer. 

      If you would like our team to try and obtain your prescription from a local or online pharmacy, click here

      That you do! You will require a matching prescription for any and all orders from

      Saxenda should be refrigerated at a temperature between 36 to 46 Fahrenheit. It should not be frozen. After administering the first injection, you can refrigerate your Saxenda or keep it at room temperature. Do not store your Saxenda in direct sunlight or at temperatures above 86 degrees F.

      You can use your Saxenda pen for 30 days. After 30 days, the medication is expired and should be discarded.

      Your Saxenda pen has a scale showing how much medication is left in the device.

      We use temperature-sensitive packaging with medical-graded gel packs to ensure it remains cool while it travels to your home. 

      We have two carriers: Canada Post and USPS. Once your order crosses the border into the US, USPS takes over the shipping responsibility. 

      Studies showed that people who took Saxenda for 56 weeks lost 5 to 10 percent of their body weight or about 12 to 23 pounds.

      The warnings about Saxenda do not include a warning against drinking alcohol. Remember: if you are taking other diabetes drugs, alcohol use increases the risk of hypoglycemia.

      The medicine is at maximum concentration 11 hours after it is injected. Check-in with your doctor within eight weeks after taking Saxenda to see if it works for you.

      If you forget to use Saxenda, inject your daily dose as soon as you remember. Then, inject your daily dose the following day,

      It would be best not to take an extra dose or double it to compensate for the missed dose.

      If you forget to take your dose for three or more days, please contact your prescribing physician to discuss getting back on track.

      Do not share any part of your Saxenda pen with another person, including the syringe, cartridge, or injection pen. If you share an injection pen with someone, you can pass infections or diseases.

      Do not use Saxenda with other weight loss medications, appetite suppressants, or diet pills.

      Call the Poison Help Line at 1-800-222-1222 or get emergency medical help.

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