Rybelsus® (Semaglutide)



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  • Rybelsus

    Rybelsus® (Semaglutide)


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    •  Box Warning

      The official box warning for Rybelsus (semaglutide) tablets, as prescribed by the FDA, alerts healthcare professionals and patients about the potential increased risk of thyroid C-cell tumors. This warning is included in the prescribing information and is based on findings from animal studies. However, it is important to clarify that the correlation between Rybelsus and thyroid tumors in humans remains unclear.

      Patients who have a personal or family history of medullary thyroid carcinoma (MTC) or those with a history of Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) are advised against using Rybelsus. Furthermore, it is not recommended as the first choice of medicine for treating diabetes.

      Rybelsus also carries warnings about other potential risks, such as pancreatitis, diabetic retinopathy, hypoglycemia, acute kidney injury, and hypersensitivity reactions. Patients with a history of pancreatitis should be particularly cautious, and the risk of hypoglycemia may increase when Rybelsus is used in combination with other medications like sulfonylureas or insulin.

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      Rybelsus® (Semaglutide)


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      •  Product Monograph

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      Medically Reviewed by

      Dr. Aaron L Wiegmann (MD, MS)

      Active Ingredient:Semaglutide
      Warnings:Possible thyroid tumours, including thyroid cancer
      Drug Type:GLP-1 receptor agonist
      Used For:Adults with type 2 diabetes
      Administration:Oral tablets (daily)
      Available Strengths:3mg, 7mg, 14mg
      Storage:Store between 68°F and 77°F (20°C and 25°C). Keep dry and away from moisture.
      Manufacturer:Novo Nordisk

      What Is Rybelsus?

      Rybelsus (semaglutide) is a brand-name diabetic medicine approved by the FDA as an effective treatment for type 2 diabetes. This oral medicine helps type 2 diabetics control their blood sugar by mimicking GLP-1, a hormone in the body. It also has tremendous results in weight-loss management. 

      Rybelsus Cost & Coupons

      The overall Rybelsus cost is insane – a 30-tablet pack that will last only a month costs close to $1,270 and accumulates to $15,000 per year. Fortunately for many patients, Diet Pens has a loophole for you!

      Diet Pens offers Rybelsus at a low price through its prescription fulfillment service. For your first purchase with Diet Pens, please be sure to use the coupon code DIET10. This coupon will give you 10% off the first time you buy Rybelsus from Canada.

      How to Use Rybelsus

      Proper usage of Rybelsus, a type 2 diabetes medicine, is essential for blood sugar control. Use Rybelsus efficiently with this guide:

      Follow Your Doctor's Orders

      The most crucial thing is to follow your doctor’s Rybelsus directions. This covers dose, timing, and other individualized advice.

      Take It Orally

      Rybelsus is a tablet. Use a glass of water to consume it as a whole. Do not crush, chew, or split the tablet—it may lose potency.

      Choose a Convenient Time

      You can take Rybelsus with or without meals, giving you daily freedom. Some people like to take it with their first meal, while others find it more convenient afterward. Choose a convenient time and stick to it.

      Establish a Routine

      Rybelsus requires consistency. To optimize blood sugar management, take Rybelsus daily at the same time. Routines help you remember medicine and control blood sugar.

      Consider Other Medications

      Be mindful of drug interactions if you use other drugs or supplements. To prevent Rybelsus interactions, take certain drugs at separate times. Do not take other GLP-1 medications (such as Trulicity and Saxenda) while you are taking Rybelsus. 

      Make Lifestyle Changes

      Rybelsus works best with a good diet and exercise. Develop a comprehensive diabetes treatment plan with your doctor that incorporates these lifestyle changes.

      Check Your Blood Sugar

      Blood sugar should be monitored regularly as instructed by your doctor. This determines Rybelsus’ efficacy and if your treatment strategy has to be changed.

      Report Side Effects

      Rybelsus is typically well-tolerated, however, be on the lookout for adverse effects. Report unusual or severe symptoms, including persistent nausea, vomiting, or stomach pain, to your doctor immediately.

      Be Patient

      Blood sugar levels may take longer to respond to Rybelsus. The drug needs time to work, so be patient. Your doctor will track and modify your progress.

      Get Regular Check-ups

      Attend frequent check-ups with your doctor to assess your progress and change your treatment plan if necessary. Open communication offers the best and safest type 2 diabetes management.

      How Rybelsus Works

      Rybelsus medication uses the body’s natural mechanisms to stabilize blood sugar. It is also a GLP-1 receptor agonist, a unique drug family functioning as a natural blood sugar regulator. For this reason, Rybelsus pills have recently become an alternative option for Ozempic and WegovyHere is how the medication works:

      • GLP-1 Receptor Agonist: Rybelsus pharmaceutically delivers GLP-1’s power, which aids in controlling blood sugar levels and leading to weight loss.
      • Increased Insulin Release: Rybelsus medication gracefully lowers blood sugar by imitating GLP-1 and increasing insulin release.
      • Glucagon Inhibition: Rybelsus inhibit glucagon is crucial to blood sugar balance. Hence, it maintains their blood sugar more effectively and predictably.
      • Delayed Gastric Emptying: Rybelsus slows this process, releasing nutrients slowly into the circulation.
      • Appetite Control: Rybelsus may affect appetite. It may help you eat better and cut calories by sending signals to the brain that you’re full, allowing blood sugar regulation and weight management.

      Rybelsus Side Effects

      Before purchasing Rybelsus, you should be aware that while some may experience adverse effects similar to any medication, many respond positively to Rybelsus, yet if side effects occur, consulting a doctor for management is essential.

      • Nausea
      • Vomiting
      • Diarrhea
      • Stomach pain
      • Reduced Appetite
      • Hypoglycemia – Low Blood Sugar
      • Pancreatitis
      • Allergic Reactions
      • Other Side Effects: Fatigue, headache, and elevated heart rate are rare adverse effects.

      If you notice any of these symptoms after taking Rybelsus medication, immediately contact your doctor. Monitor your drug reaction, modify the dose, and address any side effects or concerns with your healthcare provider.


      Drug Interactions With Rybelsus

      You must consider drug interactions while using and buying Rybelsus online. Drug interactions may impact efficacy, side effects, and safety. To guarantee your safety and enhance your treatment plan, tell your doctor about all your drugs and supplements. Use prescription Rybelsus for weight loss or type 2 diabetes with caution if you are using the following drugs:

      1. Insulin, Sulfonylureas: Semaglutide pills may raise the risk of hypoglycemia when administered with insulin or sulfonylureas such as glipizide or glyburide.
      2. Warfarin: The blood-thinning drug may interact with prescription Rybelsus, altering blood clotting. While using semaglutide tablets, your doctor may need to change your warfarin dose and check your INR (International Normalized Ratio).
      3. Digoxin: In conjunction with digoxin, Rybelsus has been reported to increase heart rate.
      4. Drugs or Medicines: Rybelsus may impair oral drug absorption by affecting stomach emptying. Take other drugs at least 30 minutes before Rybelsus to maximize their benefits.
      5. Pancreatitis Risk: Rybelsus has not been investigated in people with pancreatitis. To lessen the risk of problems, your doctor may suggest different diabetic treatments if you have pancreatitis.
      6. Herbal Supplements and OTC Drugs: Herbal supplements, vitamins, and over-the-counter drugs may interact with Rybelsus and impact blood sugar.
      7. Other Prescription Drugs: Antibiotics, antifungals, and stomach-emptying drugs may interact with Rybelsus.

      Drug interactions are individual and may not occur in everyone. Your doctor is the proper professional to monitor your status and adjust your treatment plan to guarantee your safety and enhance type 2 diabetes control. 

      Strengths and Dosages of Rybelsus Medication

      Rybelsus comes in various strengths and doses to suit Type 2 diabetic treatment programs. Strength and dose depend on your healthcare demands and blood sugar response.

      Recommended Dosages

      • 3 mg Rybelsus: This is Rybelsus’s lowest strength and frequently the first dosage. Many type 2 diabetics start with this dose to test the drug.
      • 7 mg Rybelsus: If 3 mg isn’t enough to manage your blood sugar, your doctor may suggest 7 mg. This intermediate strength stabilizes blood sugar more effectively.
      • 14 mg Rybelsus: The strongest Rybelsus is 14 mg. It is meant for those who need more rigorous blood sugar control and haven’t reached their targets with lesser doses.

      Usage Instructions

      Rybelsus weight loss and type 2 diabetes medication is usually given once a day with or without meals, depending on your treatment plan. Following your doctor’s prescription scheduling and administration recommendations is crucial.


      If you have any questions or concerns about buying Rybelsus from Canada, please don't hesitate to contact us.


      Yes, you can! We have partnered with licensed pharmacies in Canada and the UK to help Americans purchase their medication at a discounted price.

      If your prescription is at your doctor’s office or pharmacy, one of our agents can reach out to them and try to retrieve the prescription.

      To request a prescription transfer, click here

      No, we do not accept health insurance.

      If this is your first time using Diet Pens, you can use the coupon code DIET10. This will enable you to receive 10% off your first time buying Rybelsus from Canada. 

      We do occasionally provide discount codes. You can join our mailing list or contact one of our customer service representatives.

      We use Canada Post and USPS. Once your order crosses the border, the shipping responsibilities shift from Canada Post to USPS.

      Of course! As soon as your order is on its way, we will provide you with a tracking number via email.

      Rybelsus may cause weight loss of 2kg to 4kg. Research has shown that people take Rybelsus 7mg and Rybelsus 14mg for 26 weeks, and they lose an average of 5 pounds (2.3 kg) and 8.1 pounds (3.7 kg), respectively. Rybelsus may be more effective in causing weight loss in people who are overweight or experiencing digestive symptoms at the start of treatment. After eating, Rybelsus helps you feel full.

      The answer is no, you should not do that. In addition to Rybelsus 3 mg, Rybelsus 7 mg, and Rybelsus 14 mg are available in three dosage forms. Breaking and consuming the pills will not result in their effectiveness. There is an exact concentration of the drug, and if it is hindered, it will not be effective.

      Take Rybelsus only as prescribed by your doctor. There are serious side effects associated with using more than this amount.

      Overdosing on Rybelsus should be monitored for signs and symptoms of overdose. Do not take Rybelsus in excess unless advised by your doctor. The American Association of Poison Control Centers can also be reached at 800-222-1222.

      If Rybelsus is taken during pregnancy, it is unknown whether it is harmful.

      It’s harmful to have diabetes during pregnancy if it’s not well managed.
      Pregnant women or those considering pregnancy who have diabetes should discuss this with their doctors. Rybelsus treatment involves both risks and benefits, which will assist you with weighing. Rybelsus medication should not be taken while pregnant without consulting your doctor.

      Additionally, Rybelsus may pass into breast milk. Rybelsus should not be taken while breastfeeding.

      SKU: rybelsus-semaglutide-tablets Category: 
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