Zepbound

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    Zepbound

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    •  Box Warning

      The medication Zepbound (tirzepatide) carries a boxed warning regarding the risk of thyroid tumors, including thyroid cancer. This warning is based on studies conducted with rats, where tirzepatide and similar medicines caused thyroid tumors. However, it is not clear whether the same risk applies to humans using Zepbound. Due to this potential risk, Zepbound is contraindicated for individuals who have a personal or family history of a type of thyroid cancer known as medullary thyroid carcinoma (MTC), or for those with an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Patients using Zepbound are advised to be vigilant for symptoms of thyroid tumors, such as swelling or a lump in the neck, trouble swallowing, hoarseness, or shortness of breath. If such symptoms occur, immediate medical consultation is recommended.

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      Zepbound

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      Medically Reviewed by

      Dr. Ari Magill (MD, MS)

      Warnings:Possible thyroid tumors, including thyroid cancer
      Drug Type:GLP-1 receptor agonist
      Used For:Chronic weight management in adults with obesity or overweight.
      Administration:Subcutaneous Injection (once weekly)
      Available Strengths:2.5mg, 5mg, 7.5mg, 10mg, 12.5mg and 15mg
      Storage:Keep in the refrigerator between 36°F and 46°F (2°C and 8°C).
      Manufacturer:Eli Lilly

      What is Zepbound?

      Zepbound is a weight-loss drug produced by Lilly. It is a dual-agonist, meaning it activates two hormone receptors: GLP-1 and glucose-dependent insulinotropic polypeptide (GIP). 

      The overarching goal of these drugs is to treat Type-2 Diabetes and obesity (excessive body fat) in order to prevent the effects of cardiovascular disease, which is the most common cause of death in people with Type-2 Diabetes.

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      Zepbound Cost & Coupons

      Without insurance or a discount of any kind, Zepbound and many other GLP-1 antagonist drugs cost roughly $1,060 per 28-day supply, meaning a year’s supply could set you back nearly $13,000. There is also no generic or more economical version of Zepbound, as it is relatively new to the market.

      Zepbound - Where to Buy for the Best Price

      Customers who order Zepbound online from Diet Pens not only get it at the best price, but when ordering for the first time, they can save 10% by using coupon code: DIET10.

      Who Should & Shouldn’t Take Zepbound

      Zepbound is for:

      • People with obesity and additional weight-related health concerns, such as high cholesterol, Type-2 Diabetes, and others.

      Zepbound is NOT for:

      • People already taking another GLP-1 agonist
      • People under the age of 18
      • People who are pregnant
      • People who have a history of pancreatitis
      • People who have a history or (family history) of thyroid cancers, including medullary thyroid carcinoma.
      • People who have a history or a family history of a disease called Multiple Endocrine Neoplasia Syndrome type 2.

      Zepbound Side Effects

      When taking Zepbound, you can either experience side effects or an allergic reaction – seek medical attention when you notice allergic reaction symptoms.

      Common Side Effects

      The most common side effects reported by patients taking Zepbound are various stomach problems. They include the following:

      • Stomach Pain
      • Indigestion
      • Nausea
      • Diarrhea
      • Belching
      • Heartburn
      • Vomiting
      • Constipation
      • Fatigue
      • Hair Loss
      • Heartburn
      • Injection Site Reactions
      • Allergic Reactions

      Severe Side Effects

      Patients have reported Zepbound to have some more serious side effects. These including:

      • Severe Stomach Problems
      • Pancreatitis
      • Kidney Problems, Including Kidney Failure
      • Gallbladder Problems, the symptoms of which include:
        • Pain in your upper abdomen
        • Fever
        • Jaundice, which is yellowing of your skin
        • Clay-colored poop
      • Thyroid Problems, Including Thyroid Tumors and Cancer. Symptoms to look out for include:
        • Neck Swelling
        • Lump in Neck
        • Trouble Swallowing
        • Shortness of Breath
        • Hoarseness

      Less-Severe Side Effects

      Less-severe side effects do not require medical attention because they may go away as you adjust to Zepbound, or they may not be so bothersome as to require intervention. They include:

      • Upset Stomach
      • Stomach Pain
      • Acid Stomach
      • Sour Stomach
      • Persistent Belching
      • Constipation
      • Diarrhea

      Injection Site Side Effects

      If you have the following side effects at the injection site while you are taking Zepbound, you should contact your physician right away:

      • Bleeding
      • Blistering
      • Burning
      • Coldness
      • Discoloration of skin
      • Feeling of pressure
      • Hives
      • Infection
      • Inflammation
      • Itching
      • Lumps
      • Numbness or warmth
      • Pain
      • Rash
      • Redness
      • Scarring
      • Soreness
      • Stinging
      • Swelling
      • Tenderness
      • Tingling
      • Ulceration

      Serious Allergic Reaction

      The following are symptoms of a serious allergic reaction. If you have these symptoms, contact your physician right away or report to the nearest emergency room.

      • Swelling of your lips, tongue, face, or throat
      • Trouble swallowing
      • Trouble breathing
      • Very rapid heartbeat
      • Severe rash or itching
      • Fainting or dizziness

      Zepbound Drug Interactions

      Drugs.com reports that Zepbound has interactions with 396 different medications. Two medications have major interactions with Zepbound, which are bexarotene (an anti-cancer drug for the treatment of cutaneous, or skin, T cell lymphoma) and gatifloxacin, an antibiotic used to treat a wide variety of infections. Inform your doctor if taking any of those medications, as they might prescribe a different dosage or another medication.

      Any additional drugs or supplements you use, including vitamins and herbs, should also be communicated to your medical professional. Do not discontinue taking any drugs without first consulting your doctor.

      Zepbound Strengths & Dosages

      Zepbound comes in pre-filled dosage pens. It comes in the following sizes:

      • 2.5 mg in 0.5 mL
      • 5 mg in 0.5 mL
      • 7.5 mg in 0.5 mL
      • 10 mg in 0.5 mL
      • 12.5 mg in 0.5 mL
      • 15 mg in 0.5 mL

      This medication is injected under the skin once a week. If you miss a dose but are within four days after the missed dose, take it as soon as you remember. If more than four days have passed when you remember, skip the dose you missed and continue with your regular schedule. Never inject two doses of Zepbound within three days of each other.

      What dosage you receive will be determined by your doctor, likely starting at the smallest dose and increasing over time. 

      Whether you proceed to the largest dose will depend on several factors, including how your diabetes or obesity responds to the drug and the side effects you exhibit.

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      How To Use Zepbound

      Like many other GLP-1 agonist drugs, Zepbound is injected under the skin or subcutaneously. Your doctor should walk you through how to use it. In addition, you should receive a leaflet with your prescription that will explain how to use it.

      You or another person may inject Zepbound into several parts of your body, including the back of your upper arm, your thigh, or your abdomen.

      Injecting Zepbound

      1. Check over your Zepbound injection pen before use. Make sure it’s the correct dose and is not expired. Make sure it is not damaged in any way. The medicine should not be frozen, cloudy, or have any particles floating in it. It should be clear to slightly yellow and transparent.
      2. Choose your injection site. You should pick a location that has fat and not a lot of muscle, like the back of your upper arm, your thigh, or your abdomen. Pick a different injection site each week so the injection site doesn’t get too sore.
      3. The Zepbound pen has a gray base cap. Take it off, pull straight down, and throw it away. Do not touch the needle.
      4. Place the clear base of the pen on your body where you want to inject the medicine. Unlock the pen by turning the top of the pen.
      5. Press and hold the injection pen against the site for up to 10 seconds. You will hear two clicks: the first indicates the injection has started, and the second indicates the injection has finished. Another way to know the injection has finished: you should be able to see a gray plunger.
      6. Dispose of your injection pen safely. Check the FDA website to find out your state’s regulations regarding sharps disposal.

      FAQs

      Yes! If you have a valid prescription, you can purchase any of our medications.

      It takes approximately 4-10 business days. We will provide you with a tracking number as soon as it’s on its way. We highly suggest requesting text message notification updates through the tracking page.

      We can try our best! Some pharmacies allow transfers to mail-in pharmacies, while others do not. 

      For prescription transfer requests, click here

      Zepbound starts working relatively quickly to lower your blood glucose levels. It may take eight to 12 weeks to reach your A1C goal, depending on several factors like initial A1C, diet, and exercise. Weight loss effects should be noticeable after at least 16 weeks (although it will vary from person to person).

      Keep your eyes on our emails! We provide discounts throughout the year that can help you save even more money!

      Call Poison Control at 1-800-222-1222 if you believe you have taken too much Zepbound or call for emergency medical assistance at 911.

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